PyInstaller has a bunch of nice hacks built in that will supposedly make it easier to build application bundles including dependencies (like PyQt!) for Linux, Mac and MSWin. I will have to try it out soon for Pycessing.
Installing open source stuff on OSX can be a pain. MacPorts is a nice project but sometimes I don't have 3 hours to kill waiting for things to compile. Homebrew might be a decent replacement. Then again, maybe Linux is an even better replacement.
Not new, but I recently rediscovered the Radical Software magazine archive. Classic '70s new media hacking art culture, well mostly video really.
Nice little intro to using PyAudio and NumPy for procedural music. Might be interesting to take some statistical input.
Whatever you want to call it, it's pretty cool and some folks have been building an interesting scene around it:
Movid - is a back-end for CV stuff and it looks kinda nice. It's got a nice graph based GUI config and spits out JSON over a network socket. Supports multi-touch, TUIO, etc. You have to roll your own frontend though.